嫩草AV无码精品一区三区,亚洲综合五月天婷婷丁香,亚洲AV无码秘蜜桃希岛爱理

鄭重說明:

您值得信賴的中藥成分及標(biāo)準(zhǔn)合作伙伴滿足您研發(fā)和工業(yè)化需求

產(chǎn)品關(guān)鍵詞：香草酸-4-β-D-葡萄糖苷 6-甲氧基山奈酚茯苓新酸B 去甲異波爾定

guanyuwomen關(guān)于德思特

聯(lián)系方式

服務(wù)熱線：

028-8500-3950

公司傳真：	028-85589956
公司郵箱：	sales@tcmlmt.com
公司網(wǎng)址：	m.ipv16.com
公司地址：	四川省成都市溫江區(qū)?？坡肺鞫?28號(hào)5棟

發(fā)表文獻(xiàn)展示

當(dāng)前位置:首頁關(guān)于德思特 > 發(fā)表文獻(xiàn)展示 >

Discovery of minor quality evaluation marker ....

時(shí)間：2022-05-30 瀏覽次數(shù)：分享到：

Chinese patent medicines (CPMs) are popularly used in clinical practice. Though the composition is complex, the quality of CPM is usually evaluated by the contents of a few main compounds. In this study,a two-leveled metabolomics strategy was proposed to discover minor marker compounds for different CPM products. Zhenqi Fuzheng (ZQFZ) granule was studied an example, where 15 batches from 3 producers were analyzed. The samples were separated using UHPLC on an Acquity UPLC® HSS T3 column,and then detected using Q-Orbitrap-MS. In the first level, 1475 common peaks were extracted and 95 compounds were identified using diagnostic ions and a homemade database. In the second level, the data were subjected to a two-way hierarchical clustering analysis and screened by variable importance value. In total 14 marker compounds were discovered which were responsible for the grouping of different ZQFZ products. Echinacoside (22), oleoside (13), loganic acid (5), salidroside (7), ligustrosidic acid (42), 6α-hydroxygeniposide (28), and oleoside 11-methyl ester (15) could be used to reflect the quality difference for ZQFZ granule products. The proposed strategy could also contribute to the discovery of quality control markers for other CPMs.

........

2. Experimental

2.1. Chemicals and reagents

The reference compounds salidroside (R1), echinacoside (R2), oleuropein (R3), specnuezhenide (R4), nuezhenoside G13 (R5), astragaloside I (R6), astragaloside III (R7), calycosin (R8) and calycosin-7-O-β-d-glucoside (R9) were purchased from Chengdu DeSiTe Biological Technology Co., Ltd. (Chengdu, China);

........

上一篇：Discovery of a novel megakaryopoiesis enhancer, ingenol,……

下一篇：6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral ...

Afrormosine CAS:550-79-8 中藥對照品標(biāo)準(zhǔn)品

產(chǎn)品編碼：DA0040產(chǎn)品名稱：Afrormosine英文名:AfrormosineCAS登錄...